{"id":231553,"date":"2026-02-17T21:25:50","date_gmt":"2026-02-18T03:25:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/cross-disease-analysis-identifies-the-inflammatome-as-a-transcriptional-program-of-inflammation"},"modified":"2026-02-17T21:25:50","modified_gmt":"2026-02-18T03:25:50","slug":"cross-disease-analysis-identifies-the-inflammatome-as-a-transcriptional-program-of-inflammation","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/cross-disease-analysis-identifies-the-inflammatome-as-a-transcriptional-program-of-inflammation","title":{"rendered":"Cross-disease analysis identifies the inflammatome as a transcriptional program of inflammation"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cross-disease-analysis-identifies-the-inflammatome-as-a-transcriptional-program-of-inflammation2.jpg\"><\/a><\/p>\n<p>D\u00edaz-Pin\u00e9s Cort et al. identify a 100-gene inflammation signature and a broader 2,000-gene inflammatome, consistently upregulated across inflammatory diseases and tissues. They show that these resources can detect inflammation in transcriptomic and proteomic datasets, distinguish disease-specific signals from general inflammation, and generate sample-wise inflammation scores correlated with disease activity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>D\u00edaz-Pin\u00e9s Cort et al. identify a 100-gene inflammation signature and a broader 2,000-gene inflammatome, consistently upregulated across inflammatory diseases and tissues. They show that these resources can detect inflammation in transcriptomic and proteomic datasets, distinguish disease-specific signals from general inflammation, and generate sample-wise inflammation scores correlated with disease activity.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-231553","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231553","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231553"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231553\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231553"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231553"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231553"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}