{"id":231287,"date":"2026-02-13T13:10:20","date_gmt":"2026-02-13T19:10:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/lateral-habenula-and-periaqueductal-gray-neurons-signal-reward-prediction-error-and-continuity-of-reward-expectancy-to-drive-reward-seeking-behavior"},"modified":"2026-02-13T13:10:20","modified_gmt":"2026-02-13T19:10:20","slug":"lateral-habenula-and-periaqueductal-gray-neurons-signal-reward-prediction-error-and-continuity-of-reward-expectancy-to-drive-reward-seeking-behavior","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/lateral-habenula-and-periaqueductal-gray-neurons-signal-reward-prediction-error-and-continuity-of-reward-expectancy-to-drive-reward-seeking-behavior","title":{"rendered":"Lateral habenula and periaqueductal gray neurons signal reward prediction error and continuity of reward expectancy to drive reward-seeking behavior"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/lateral-habenula-and-periaqueductal-gray-neurons-signal-reward-prediction-error-and-continuity-of-reward-expectancy-to-drive-reward-seeking-behavior2.jpg\"><\/a><\/p>\n<p>Lee and Hikosaka show how animals overcome challenges and ultimately achieve goals. They find that LHb and PAG neurons encode prediction errors and the continuity of reward expectancy, with tonic PAG activity sustaining reward expectancy despite prediction errors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lee and Hikosaka show how animals overcome challenges and ultimately achieve goals. They find that LHb and PAG neurons encode prediction errors and the continuity of reward expectancy, with tonic PAG activity sustaining reward expectancy despite prediction errors.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-231287","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231287","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231287"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231287\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231287"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231287"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231287"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}