{"id":231283,"date":"2026-02-13T13:05:48","date_gmt":"2026-02-13T19:05:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/single-gene-found-to-influence-gut-bacteria-balance-and-ibd-susceptibility"},"modified":"2026-02-13T13:05:48","modified_gmt":"2026-02-13T19:05:48","slug":"single-gene-found-to-influence-gut-bacteria-balance-and-ibd-susceptibility","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/single-gene-found-to-influence-gut-bacteria-balance-and-ibd-susceptibility","title":{"rendered":"Single gene found to influence gut bacteria balance and IBD susceptibility"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/single-gene-found-to-influence-gut-bacteria-balance-and-ibd-susceptibility2.jpg\"><\/a><\/p>\n<p>Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD).<\/p>\n<p>Led by Declan McCole, a professor of biomedical sciences in the School of Medicine, the studies show that when PTPN2 does not function properly, the gut becomes more vulnerable to infection and inflammation.<\/p>\n<p>People with IBD often have higher levels of AIEC, a harmful type of E. coli bacteria. AIEC can attach to the gut lining, invade gut cells, damage the gut\u2019s protective barrier, and worsen inflammation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD). Led by Declan McCole, a professor of biomedical sciences in the School of Medicine, the studies show [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-231283","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231283","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231283"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231283\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231283"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231283"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}