{"id":231264,"date":"2026-02-13T01:28:30","date_gmt":"2026-02-13T07:28:30","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/functional-characterization-of-a-de-novo-scn2a-mixed-variant-linked-to-early-infantile-developmental-and-epileptic-encephalopathy"},"modified":"2026-02-13T01:28:30","modified_gmt":"2026-02-13T07:28:30","slug":"functional-characterization-of-a-de-novo-scn2a-mixed-variant-linked-to-early-infantile-developmental-and-epileptic-encephalopathy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/functional-characterization-of-a-de-novo-scn2a-mixed-variant-linked-to-early-infantile-developmental-and-epileptic-encephalopathy","title":{"rendered":"Functional Characterization of a De Novo SCN2A Mixed Variant Linked to Early Infantile Developmental and Epileptic Encephalopathy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/functional-characterization-of-a-de-novo-scn2a-mixed-variant-linked-to-early-infantile-developmental-and-epileptic-encephalopathy2.jpg\"><\/a><\/p>\n<p>Background and ObjectivesPathogenic variants in the SCN2A gene, encoding the \u03b1-subunit type 2 of the voltage-gated sodium channel NaV1.2, cause a phenotypic spectrum including 4 major disorders as benign familial infantile seizures, developmental and\u2026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background and ObjectivesPathogenic variants in the SCN2A gene, encoding the \u03b1-subunit type 2 of the voltage-gated sodium channel NaV1.2, cause a phenotypic spectrum including 4 major disorders as benign familial infantile seizures, developmental and\u2026<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-231264","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231264"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231264\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}