{"id":23112,"date":"2016-03-04T08:47:49","date_gmt":"2016-03-04T16:47:49","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/2016\/03\/researcher-develops-technique-for-enhancing-gene-therapy"},"modified":"2017-06-04T20:07:51","modified_gmt":"2017-06-05T03:07:51","slug":"researcher-develops-technique-for-enhancing-gene-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2016\/03\/researcher-develops-technique-for-enhancing-gene-therapy","title":{"rendered":"Researcher develops technique for enhancing gene therapy"},"content":{"rendered":"<p><a class=\"blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researcher-develops-technique-for-enhancing-gene-therapy.jpg\"><\/a><\/p>\n<p>Using his knowledge of how genes are organized and repaired in human cells, Dr. Graham Dellaire, Dalhousie Medical School\u2019s Cameron Research Scientist in Cancer Biology, has developed a technique that could make gene therapy more effective and safer to use. His work was recently published in <i>Nucleic Acids Research<\/i> and <i>Nature<\/i>.<\/p>\n<p>CRISPR, named 2015\u2019s breakthrough discovery of the year, stands for \u201cClustered Regularly-Interspaced Short Palindromic Repeats.\u201d It can accurately target and edit DNA, offering the potential to cure genetic diseases and find new treatments for cancer.<\/p>\n<p>To apply CRISPR in non-dividing cells\u2014such as those in muscle and brain tissue\u2014researchers must first make them behave like cells that divide. They do this by turning on a cellular process called homologous recombination, which protects DNA; the recombination allows a cell\u2019s genes to be manipulated and rearranged without the possibility of causing more harm than good.<\/p>\n<p><!-- Link: <a href=\"http:\/\/phys.org\/news\/2016-03-technique-gene-therapy.html\">http:\/\/phys.org\/news\/2016&#45;03-technique-gene-therapy.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using his knowledge of how genes are organized and repaired in human cells, Dr. Graham Dellaire, Dalhousie Medical School\u2019s Cameron Research Scientist in Cancer Biology, has developed a technique that could make gene therapy more effective and safer to use. His work was recently published in Nucleic Acids Research and Nature. CRISPR, named 2015\u2019s breakthrough [\u2026]<\/p>\n","protected":false},"author":367,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-23112","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/23112","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/367"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=23112"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/23112\/revisions"}],"predecessor-version":[{"id":68147,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/23112\/revisions\/68147"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=23112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=23112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=23112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}