{"id":230805,"date":"2026-02-07T09:29:32","date_gmt":"2026-02-07T15:29:32","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/lactobacillus-delbrueckii-surface-protein-p4430-attenuates-intestinal-inflammation-by-modulating-macrophage-polarization-via-mincle"},"modified":"2026-02-07T09:29:32","modified_gmt":"2026-02-07T15:29:32","slug":"lactobacillus-delbrueckii-surface-protein-p4430-attenuates-intestinal-inflammation-by-modulating-macrophage-polarization-via-mincle","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/lactobacillus-delbrueckii-surface-protein-p4430-attenuates-intestinal-inflammation-by-modulating-macrophage-polarization-via-mincle","title":{"rendered":"Lactobacillus delbrueckii surface protein P4430 attenuates intestinal inflammation by modulating macrophage polarization via Mincle"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/lactobacillus-delbrueckii-surface-protein-p4430-attenuates-intestinal-inflammation-by-modulating-macrophage-polarization-via-mincle2.jpg\"><\/a><\/p>\n<p>Zhang et al. reveal that <i><i>Lactobacillus<\/i> <i>del <i>brueckii<\/i><\/i><\/i> ameliorates ulcerative colitis by suppressing proinflammatory macrophages via its surface protein, P4430. This mechanism, which involves targeting the host Mincle receptor, defines a microbial strategy for combating intestinal inflammation and suggests a potential therapeutic path.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zhang et al. reveal that Lactobacillus del brueckii ameliorates ulcerative colitis by suppressing proinflammatory macrophages via its surface protein, P4430. This mechanism, which involves targeting the host Mincle receptor, defines a microbial strategy for combating intestinal inflammation and suggests a potential therapeutic path.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-230805","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/230805","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=230805"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/230805\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=230805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=230805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=230805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}