{"id":230616,"date":"2026-02-05T13:14:37","date_gmt":"2026-02-05T19:14:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/phase-1-and-preclinical-studies-reveal-safety-pharmacokinetics-and-efficacy-of-intranasal-delivery-of-the-influenza-antibody-cr9114"},"modified":"2026-02-05T13:14:37","modified_gmt":"2026-02-05T19:14:37","slug":"phase-1-and-preclinical-studies-reveal-safety-pharmacokinetics-and-efficacy-of-intranasal-delivery-of-the-influenza-antibody-cr9114","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/phase-1-and-preclinical-studies-reveal-safety-pharmacokinetics-and-efficacy-of-intranasal-delivery-of-the-influenza-antibody-cr9114","title":{"rendered":"Phase 1 and preclinical studies reveal safety, pharmacokinetics, and efficacy of intranasal delivery of the influenza antibody CR9114"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/phase-1-and-preclinical-studies-reveal-safety-pharmacokinetics-and-efficacy-of-intranasal-delivery-of-the-influenza-antibody-cr91142.jpg\"><\/a><\/p>\n<p>An intranasal flu antibody can protect against both influenza A and B in mice and nonhuman primates and is safe in humans, according to new preclinical experiments and two phase one clinical trials published in <i>Science <\/i>TranslationalMedicine.<\/p>\n<hr>\n<p>Intranasal CR9114 is safe in humans, and twice-daily dosing confers protection against influenza virus challenge in macaques.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An intranasal flu antibody can protect against both influenza A and B in mice and nonhuman primates and is safe in humans, according to new preclinical experiments and two phase one clinical trials published in Science TranslationalMedicine. Intranasal CR9114 is safe in humans, and twice-daily dosing confers protection against influenza virus challenge in macaques.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-230616","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/230616","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=230616"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/230616\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=230616"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=230616"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=230616"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}