{"id":229952,"date":"2026-01-28T01:23:06","date_gmt":"2026-01-28T07:23:06","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/data-driven-3d-chromosome-model-reveals-structural-and-dynamic-features-of-dna"},"modified":"2026-01-28T01:23:06","modified_gmt":"2026-01-28T07:23:06","slug":"data-driven-3d-chromosome-model-reveals-structural-and-dynamic-features-of-dna","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/data-driven-3d-chromosome-model-reveals-structural-and-dynamic-features-of-dna","title":{"rendered":"Data-driven 3D chromosome model reveals structural and dynamic features of DNA"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/data-driven-3d-chromosome-model-reveals-structural-and-dynamic-features-of-dna2.jpg\"><\/a><\/p>\n<p>Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren\u2019t used as often. Understanding the complexity of these structures has been challenging; chromosomes are large systems, and deciphering the structure and dynamics requires a combination of experimental data and theoretical approaches.<\/p>\n<p>The FI-Chrom method, described in a recent publication by Rice\u2019s Jos\u00e9 Onuchic and Vin\u00edcius Contessoto, is a new and effective approach for creating 3D maps of chromosomes from real-world data.<\/p>\n<p>The study is <a href=\"https:\/\/pnas.org\/doi\/10.1073\/pnas.2530583123\" target=\"_blank\">published<\/a> in the journal Proceedings of the National Academy of Sciences.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren\u2019t used as often. Understanding the complexity of these structures has been challenging; chromosomes are large systems, and deciphering the structure and dynamics requires [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-229952","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229952"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229952\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229952"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229952"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}