{"id":229933,"date":"2026-01-27T21:10:26","date_gmt":"2026-01-28T03:10:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/abstract-providing-the-first-comprehensive-quantitative-proteomics-data-for-primary-cd34-cells-from-human-myelodysplastic-syndrome-specimens"},"modified":"2026-01-27T21:10:26","modified_gmt":"2026-01-28T03:10:26","slug":"abstract-providing-the-first-comprehensive-quantitative-proteomics-data-for-primary-cd34-cells-from-human-myelodysplastic-syndrome-specimens","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/abstract-providing-the-first-comprehensive-quantitative-proteomics-data-for-primary-cd34-cells-from-human-myelodysplastic-syndrome-specimens","title":{"rendered":"Abstract: Providing the first comprehensive quantitative proteomics data for primary CD34+ cells from human myelodysplastic syndrome specimens"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract56.jpg\"><\/a><\/p>\n<p>John D. Crispino &amp; team suggest that suppression of the substrate receptor <i>FBXO11 <\/i>causes inefficient ubiquitylation of NPM1, contributing to MDS pathogenesis:<\/p>\n<p>The image shows stronger correlation of NPM1 (magenta) and <i>FBXO11<\/i> (green) in the nucleoplasm of CD34+ cells compared with the nucleolar subcompartment.<\/p>\n<hr>\n<p>\n<sup>10 <\/sup>Cyrus Tang Medical Institute, Suzhou Medical Collage, Soochow University, Suzhou, Jiangsu Province, China.<\/p>\n<p><sup>11 <\/sup>Department of Pathology, Northwestern University, Chicago, Illinois, USA.<\/p>\n<p><sup>12 <\/sup>Department of Pathology, Division of Comparative Pathology, St. Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>John D. Crispino &amp; team suggest that suppression of the substrate receptor FBXO11 causes inefficient ubiquitylation of NPM1, contributing to MDS pathogenesis: The image shows stronger correlation of NPM1 (magenta) and FBXO11 (green) in the nucleoplasm of CD34+ cells compared with the nucleolar subcompartment. 10 Cyrus Tang Medical Institute, Suzhou Medical Collage, Soochow University, Suzhou, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-229933","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229933"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229933\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229933"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}