{"id":229702,"date":"2026-01-24T00:15:47","date_gmt":"2026-01-24T06:15:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/distinct-sox9-single-molecule-dynamics-characterize-adult-differentiation-and-fetal-like-reprogrammed-states-in-intestinal-organoids"},"modified":"2026-01-24T00:15:47","modified_gmt":"2026-01-24T06:15:47","slug":"distinct-sox9-single-molecule-dynamics-characterize-adult-differentiation-and-fetal-like-reprogrammed-states-in-intestinal-organoids","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/distinct-sox9-single-molecule-dynamics-characterize-adult-differentiation-and-fetal-like-reprogrammed-states-in-intestinal-organoids","title":{"rendered":"Distinct SOX9 single-molecule dynamics characterize adult differentiation and fetal-like reprogrammed states in intestinal organoids"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/distinct-sox9-single-molecule-dynamics-characterize-adult-differentiation-and-fetal-like-reprogrammed-states-in-intestinal-organoids2.jpg\"><\/a><\/p>\n<p>New organoid research published in Stem Cell Reports:<\/p>\n<p>Cell press | gairdner foundation | sickkids foundation | california institute for regenerative medicine | uni bayreuth.<\/p>\n<hr>\n<p>Walther and colleagues employed an automated live-cell single-molecule tracking pipeline to study the diffusive behavior of the transcription factor SOX9 during adult differentiation and fetal-like reprogrammed states in intestinal organoid models. The authors linked distinct fractions of chromatin-bound SOX9 molecules to specific cellular states in enteroid monolayers, thereby paving the way to unravel molecular mechanisms underlying differentiation and organoid phenotypes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New organoid research published in Stem Cell Reports: Cell press | gairdner foundation | sickkids foundation | california institute for regenerative medicine | uni bayreuth. Walther and colleagues employed an automated live-cell single-molecule tracking pipeline to study the diffusive behavior of the transcription factor SOX9 during adult differentiation and fetal-like reprogrammed states in intestinal organoid [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,6],"tags":[],"class_list":["post-229702","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229702"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229702\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}