{"id":229642,"date":"2026-01-23T01:27:53","date_gmt":"2026-01-23T07:27:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/a-new-atlas-could-help-guide-researchers-studying-neurological-disease"},"modified":"2026-01-23T01:27:53","modified_gmt":"2026-01-23T07:27:53","slug":"a-new-atlas-could-help-guide-researchers-studying-neurological-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/a-new-atlas-could-help-guide-researchers-studying-neurological-disease","title":{"rendered":"A new atlas could help guide researchers studying neurological disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-new-atlas-could-help-guide-researchers-studying-neurological-disease.jpg\"><\/a><\/p>\n<p>Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break down or get overwhelmed, it can increase the risk of Alzheimer\u2019s, Parkinson\u2019s, and other neurological disorders.<\/p>\n<p>\u201cLysosomal function is essential for brain health, and mutations in lysosomal genes are risk factors for neurodegenerative diseases,\u201d said Monther Abu-Remaileh, a Wu Tsai Neuro affiliate and an assistant professor of chemical engineering in the Stanford School of Engineering and an assistant professor of genetics in the Stanford School of Medicine.<\/p>\n<p>The trouble is, scientists aren\u2019t sure exactly how lysosomes do their work, what\u2019s going wrong with lysosomes that leads to neurodegeneration\u2014or even in which cell types neurodegenerative disease begins. There might even be other lysosomal disorders yet to be discovered.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break down or get overwhelmed, it can increase the risk of Alzheimer\u2019s, Parkinson\u2019s, and other neurological disorders. \u201cLysosomal function is essential for brain health, and mutations in [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,19,412,1495,47],"tags":[],"class_list":["post-229642","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-chemistry","category-genetics","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229642"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229642\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229642"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229642"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}