{"id":229531,"date":"2026-01-21T21:30:47","date_gmt":"2026-01-22T03:30:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/organoid-derived-alveolar-cells-differentiate-on-a-stretchable-microfluidic-device-and-show-force-dependent-susceptibility-to"},"modified":"2026-01-21T21:30:47","modified_gmt":"2026-01-22T03:30:47","slug":"organoid-derived-alveolar-cells-differentiate-on-a-stretchable-microfluidic-device-and-show-force-dependent-susceptibility-to","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/organoid-derived-alveolar-cells-differentiate-on-a-stretchable-microfluidic-device-and-show-force-dependent-susceptibility-to","title":{"rendered":"Organoid-derived alveolar cells differentiate on a stretchable microfluidic device and show force-dependent susceptibility to"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/organoid-derived-alveolar-cells-differentiate-on-a-stretchable-microfluidic-device-and-show-force-dependent-susceptibility-to.jpg\"><\/a><\/p>\n<p>Mechanical strain exacerbates <i>Pseudomonas<\/i> infection in an organoid-based pneumonia-on-a-chip model.<\/p>\n<p>In this Research Letter, Geraldine Nouailles &amp; team use an advanced human lung-on-a-chip model to show that increased mechanical strain can make the lungs more vulnerable to harmful bacteria such as <i><i>Pseudomonas<\/i> aeruginosa<\/i>.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, Department of Infectious Diseases, Respiratory Medicine and Critical Care, Berlin, Germany.<\/p>\n<p><sup>2<\/sup>Bundeswehr Hospital Berlin, Department of Internal Medicine, Berlin, Germany.<\/p>\n<p><sup>3<\/sup>Universit\u00e4t Leipzig, ScaDS.AI, Institute for Medical Informatics, Statistics, and Epidemiology, Leipzig, Germany.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mechanical strain exacerbates Pseudomonas infection in an organoid-based pneumonia-on-a-chip model. In this Research Letter, Geraldine Nouailles &amp; team use an advanced human lung-on-a-chip model to show that increased mechanical strain can make the lungs more vulnerable to harmful bacteria such as Pseudomonas aeruginosa. 1Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, Department of Infectious Diseases, Respiratory Medicine and Critical [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-229531","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229531"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229531\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229531"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229531"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}