{"id":229410,"date":"2026-01-20T17:06:48","date_gmt":"2026-01-20T23:06:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/turning-mri-into-a-quantitative-microscope-to-detect-white-matter-injury"},"modified":"2026-01-20T17:06:48","modified_gmt":"2026-01-20T23:06:48","slug":"turning-mri-into-a-quantitative-microscope-to-detect-white-matter-injury","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/turning-mri-into-a-quantitative-microscope-to-detect-white-matter-injury","title":{"rendered":"Turning MRI into a quantitative microscope to detect white matter injury"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/turning-mri-into-a-quantitative-microscope-to-detect-white-matter-injury.jpg\"><\/a><\/p>\n<p>Early diagnosis and noninvasive monitoring of neurological disorders require sensitivity to elusive cellular-level alterations that emerge much earlier than volumetric changes observable with millimeter-resolution medical imaging.<\/p>\n<p>Morphological changes in axons\u2014the tube-like projections of neurons that transmit electrical signals and constitute the bulk of the brain\u2019s white matter\u2014are a common hallmark of a wide range of neurological disorders, as well as normal development and aging.<\/p>\n<p>A study from the University of Eastern Finland (UEF) and the New York University (NYU) Grossman School of Medicine establishes a direct analytical link between the axonal microgeometry and noninvasive, millimeter-scale diffusion MRI (dMRI) signals\u2014diffusion MRI measures the diffusion of water molecules within biological tissues and is sensitive to tissue microstructure.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Early diagnosis and noninvasive monitoring of neurological disorders require sensitivity to elusive cellular-level alterations that emerge much earlier than volumetric changes observable with millimeter-resolution medical imaging. Morphological changes in axons\u2014the tube-like projections of neurons that transmit electrical signals and constitute the bulk of the brain\u2019s white matter\u2014are a common hallmark of a wide range of [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-229410","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229410","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229410"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229410\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229410"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229410"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229410"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}