{"id":229402,"date":"2026-01-20T09:12:35","date_gmt":"2026-01-20T15:12:35","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/proton-beam-vs-intensity-modulated-radiotherapy-in-olfactory-neuroblastoma"},"modified":"2026-01-20T09:12:35","modified_gmt":"2026-01-20T15:12:35","slug":"proton-beam-vs-intensity-modulated-radiotherapy-in-olfactory-neuroblastoma","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/proton-beam-vs-intensity-modulated-radiotherapy-in-olfactory-neuroblastoma","title":{"rendered":"Proton Beam vs Intensity-Modulated Radiotherapy in Olfactory Neuroblastoma"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/proton-beam-vs-intensity-modulated-radiotherapy-in-olfactory-neuroblastoma2.png\"><\/a><\/p>\n<p>In patients with advanced olfactory neuroblastoma, IMRT and PBRT yielded similar long-term outcomes and rates of grade 2 or higher radiation-related adverse events. Theoretical benefits of PBRT\u2014such as organ sparing\u2014require further study to clarify potential clinical advantages.<\/p>\n<hr>\n<p>\n<strong>Question<\/strong> Does adjuvant proton beam radiotherapy (PBRT) provide equivalent oncologic effectiveness while reducing radiation toxic effects compared with adjuvant intensity-modulated radiotherapy (IMRT) for patients with olfactory neuroblastoma (ONB)?<\/p>\n<p><strong>Findings<\/strong> In this propensity score\u2013matched cohort study of 54 patients, patients treated with adjuvant IMRT and PBRT had similar rates of radiation toxic effects and no statistical difference in overall survival and recurrence-free survival.<\/p>\n<p><strong>Meaning<\/strong> PBRT may not improve overall survival, recurrence-free survival, or radiation toxic effects relative to IMRT for patients with ONB.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In patients with advanced olfactory neuroblastoma, IMRT and PBRT yielded similar long-term outcomes and rates of grade 2 or higher radiation-related adverse events. Theoretical benefits of PBRT\u2014such as organ sparing\u2014require further study to clarify potential clinical advantages. Question Does adjuvant proton beam radiotherapy (PBRT) provide equivalent oncologic effectiveness while reducing radiation toxic effects compared with [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-229402","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229402","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229402"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229402\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229402"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229402"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229402"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}