{"id":229233,"date":"2026-01-17T13:08:04","date_gmt":"2026-01-17T19:08:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/lymph-node-dissection-guidelines-and-survival-in-lung-adenocarcinoma"},"modified":"2026-01-17T13:08:04","modified_gmt":"2026-01-17T19:08:04","slug":"lymph-node-dissection-guidelines-and-survival-in-lung-adenocarcinoma","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/lymph-node-dissection-guidelines-and-survival-in-lung-adenocarcinoma","title":{"rendered":"Lymph Node Dissection Guidelines and Survival in Lung Adenocarcinoma"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/lymph-node-dissection-guidelines-and-survival-in-lung-adenocarcinoma2.png\"><\/a><\/p>\n<p>Guideline-adherent lymph node dissection provided a small survival benefit for patients with high-grade or no lepidic pattern LungAdenocarcinoma, but not for those with lepidic pattern alone.<\/p>\n<hr>\n<p>Importance Lymph node dissection for early-stage lung adenocarcinoma is controversial. Histologic pattern subtyping reveals heterogeneity of lung adenocarcinoma, yet its association with lymph node involvement and dissection is understudied.<\/p>\n<p>Objective To assess the association between guideline-adherent lymph node dissection, histologic pattern subtyping, and overall survival in patients with clinical T1N0M0 lung adenocarcinoma.<\/p>\n<p><strong>Design, Setting, and Participants<\/strong> This multicenter cohort study used data from the National Cancer Center LungReal database, a multicenter, electronic health records-based database for patients undergoing surgery for lung cancer, from January 2014 to December 2021, with the last follow-up in December 2022. Patients were categorized based on histologic pattern of adenocarcinoma into 2 groups: lepidic without high-grade pattern, and high-grade or no lepidic pattern. The data analysis was performed from April to November 2025.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Guideline-adherent lymph node dissection provided a small survival benefit for patients with high-grade or no lepidic pattern LungAdenocarcinoma, but not for those with lepidic pattern alone. Importance Lymph node dissection for early-stage lung adenocarcinoma is controversial. Histologic pattern subtyping reveals heterogeneity of lung adenocarcinoma, yet its association with lymph node involvement and dissection is understudied. [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-229233","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229233","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=229233"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/229233\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=229233"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=229233"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=229233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}