{"id":228948,"date":"2026-01-13T17:05:29","date_gmt":"2026-01-13T23:05:29","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/abstract-car-t-treatment-has-improved-patient-survival-but-some-patients-develop-cytokine-release-syndrome-and-hematologic-toxicities"},"modified":"2026-01-13T17:05:29","modified_gmt":"2026-01-13T23:05:29","slug":"abstract-car-t-treatment-has-improved-patient-survival-but-some-patients-develop-cytokine-release-syndrome-and-hematologic-toxicities","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/abstract-car-t-treatment-has-improved-patient-survival-but-some-patients-develop-cytokine-release-syndrome-and-hematologic-toxicities","title":{"rendered":"Abstract: CAR-T treatment has improved patient survival, but some patients develop cytokine release syndrome and hematologic toxicities"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract46.jpg\"><\/a><\/p>\n<p>Here, Marco L. Davila &amp; team recapitulate these high-grade toxicities in mice, revealing Th1-Th17 imbalance drives the co-occurrence of CRS and neutropenia; effects that could be prevented with IFNg blockade.<\/p>\n<hr>\n<p>\n<sup>4<\/sup>Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.<\/p>\n<p><sup>5<\/sup>University of Florida College of Medicine, Division of Hematology-Oncology, Gainesville, Florida, USA.<\/p>\n<p><sup>6<\/sup>Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center &amp; Research Institute, Tampa, Florida, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here, Marco L. Davila &amp; team recapitulate these high-grade toxicities in mice, revealing Th1-Th17 imbalance drives the co-occurrence of CRS and neutropenia; effects that could be prevented with IFNg blockade. 4Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA. 5University of Florida College of Medicine, Division of Hematology-Oncology, Gainesville, Florida, USA. 6Department [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-228948","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228948"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228948\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}