{"id":228834,"date":"2026-01-11T21:25:23","date_gmt":"2026-01-12T03:25:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/sequence-variants-in-small-cag-repeat-expansions-of-the-htt-gene-and-disease-onset-and-progression-in-huntington-disease"},"modified":"2026-01-11T21:25:23","modified_gmt":"2026-01-12T03:25:23","slug":"sequence-variants-in-small-cag-repeat-expansions-of-the-htt-gene-and-disease-onset-and-progression-in-huntington-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/sequence-variants-in-small-cag-repeat-expansions-of-the-htt-gene-and-disease-onset-and-progression-in-huntington-disease","title":{"rendered":"Sequence Variants in Small CAG Repeat Expansions of the HTT Gene and Disease Onset and Progression in Huntington Disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/sequence-variants-in-small-cag-repeat-expansions-of-the-htt-gene-and-disease-onset-and-progression-in-huntington-disease2.jpg\"><\/a><\/p>\n<p>Background and ObjectivesHuntington disease is an autosomal dominant neurologic disorder caused by an unstable cytosine-adenine-guanine (CAG) expansion (&gt;35 CAG) in the HTT gene. The CAG repeat length is the major determinant of disease onset and\u2026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background and ObjectivesHuntington disease is an autosomal dominant neurologic disorder caused by an unstable cytosine-adenine-guanine (CAG) expansion (&gt;35 CAG) in the HTT gene. The CAG repeat length is the major determinant of disease onset and\u2026<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-228834","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228834"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228834\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}