{"id":228678,"date":"2026-01-10T01:02:39","date_gmt":"2026-01-10T07:02:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/new-breakthrough-to-restore-aging-joints-could-help-treat-osteoarthritis"},"modified":"2026-01-10T01:02:39","modified_gmt":"2026-01-10T07:02:39","slug":"new-breakthrough-to-restore-aging-joints-could-help-treat-osteoarthritis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/new-breakthrough-to-restore-aging-joints-could-help-treat-osteoarthritis","title":{"rendered":"New Breakthrough to Restore Aging Joints Could Help Treat Osteoarthritis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-breakthrough-to-restore-aging-joints-could-help-treat-osteoarthritis2.jpg\"><\/a><\/p>\n<p>A study in mice by researchers from Stanford University has traced the loss of cartilage that comes with aging to a single protein, pointing to treatments that may one day restore mobility and ease discomfort in seniors.<\/p>\n<p>The protein 15-PGDH has previously been <a href=\"https:\/\/doi.org\/10.1038\/d41573-025-00209-5\">extensively linked to aging<\/a>: it becomes more abundant as we get older, and interferes with the molecules that repair tissue and reduce inflammation.<\/p>\n<p>That led scientists to consider whether 15-PGDH might be involved in osteoarthritis, where stress on joints leads to the breakdown <a href=\"https:\/\/en.wikipedia.org\/wiki\/Collagen\">of collagen<\/a> in cartilage, causing inflammation and pain.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study in mice by researchers from Stanford University has traced the loss of cartilage that comes with aging to a single protein, pointing to treatments that may one day restore mobility and ease discomfort in seniors. The protein 15-PGDH has previously been extensively linked to aging: it becomes more abundant as we get older, [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1522,269],"tags":[],"class_list":["post-228678","post","type-post","status-publish","format-standard","hentry","category-innovation","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228678"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228678\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}