{"id":228597,"date":"2026-01-08T21:26:58","date_gmt":"2026-01-09T03:26:58","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/enhanced-non-enzymatic-h2s-generation-extends-lifespan-and-healthspan-in-male-mice"},"modified":"2026-01-08T21:26:58","modified_gmt":"2026-01-09T03:26:58","slug":"enhanced-non-enzymatic-h2s-generation-extends-lifespan-and-healthspan-in-male-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/enhanced-non-enzymatic-h2s-generation-extends-lifespan-and-healthspan-in-male-mice","title":{"rendered":"Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/enhanced-non-enzymatic-h2s-generation-extends-lifespan-and-healthspan-in-male-mice2.jpg\"><\/a><\/p>\n<p>C\u00e1liz-Molina et al. demonstrate that hydrogen sulfide generators found in garlic extend lifespan and enhance metabolic, neurocognitive, and locomotor function in male mice. These molecules induce hepatic lipid-droplet remodeling and modulate aging-associated pathways at transcriptomic, proteomic, and persulfidomic levels. In humans, increased cysteine persulfidation correlates with relevant aspects of health.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>C\u00e1liz-Molina et al. demonstrate that hydrogen sulfide generators found in garlic extend lifespan and enhance metabolic, neurocognitive, and locomotor function in male mice. These molecules induce hepatic lipid-droplet remodeling and modulate aging-associated pathways at transcriptomic, proteomic, and persulfidomic levels. In humans, increased cysteine persulfidation correlates with relevant aspects of health.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[],"class_list":["post-228597","post","type-post","status-publish","format-standard","hentry","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228597"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228597\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}