{"id":228520,"date":"2026-01-07T13:07:57","date_gmt":"2026-01-07T19:07:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/human-t-cell-receptor-cd3-complex-structure-unraveled"},"modified":"2026-01-07T13:07:57","modified_gmt":"2026-01-07T19:07:57","slug":"human-t-cell-receptor-cd3-complex-structure-unraveled","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/human-t-cell-receptor-cd3-complex-structure-unraveled","title":{"rendered":"Human T-cell receptor\u2013CD3 complex structure unraveled!"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/human-t-cell-receptor-cd3-complex-structure-unraveled2.jpg\"><\/a><\/p>\n<p>Mean motor disconnectivity (MMD), evaluated on MRI imaging, explains additional variability in skilled hand function after subacute stroke, beyond motor evoked potential status and corticospinal tract lesion load.<\/p>\n<hr>\n<p>BACKGROUND: Persistent compromised hand function is one of the most common long-term deficits after stroke. It is related to dysfunction of the primary motor cortex (M1) and corticospinal tract (CST) as assessed by magnetic resonance imaging-derived estimates of CST lesion load or by transcranial magnetic stimulation-derived measures, such as motor evoked potential (MEP) status. However, substantial interindividual variability remains with these measures. We tested whether a novel measure, mean motor disconnectivity (MMD), explains additional variation in the hand function of subacute stroke patients. METHODS: Thirty-two participants (15 M\/17 F; age, 58.6\u00b19.65 years) after unilateral ischemic stroke involving the CST and related upper extremity weakness were studied within 4 weeks of stroke in a cross-sectional study design at Emory University between 2015 and 2021.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mean motor disconnectivity (MMD), evaluated on MRI imaging, explains additional variability in skilled hand function after subacute stroke, beyond motor evoked potential status and corticospinal tract lesion load. BACKGROUND: Persistent compromised hand function is one of the most common long-term deficits after stroke. It is related to dysfunction of the primary motor cortex (M1) and [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-228520","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228520"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228520\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}