{"id":228429,"date":"2026-01-06T10:12:10","date_gmt":"2026-01-06T16:12:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/abstract-can-we-help-fat-cells-get-in-shape-in-diabetes"},"modified":"2026-01-06T10:12:10","modified_gmt":"2026-01-06T16:12:10","slug":"abstract-can-we-help-fat-cells-get-in-shape-in-diabetes","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/abstract-can-we-help-fat-cells-get-in-shape-in-diabetes","title":{"rendered":"Abstract: Can we help fat cells get in shape in diabetes?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract42.jpg\"><\/a><\/p>\n<p>Here, James C. Lo &amp; team identify <i>FAM20C<\/i> as a key mediator of obesity-induced adipocyte dysfunction and inflammation, suggesting its inhibition as a potential therapy for Type2 <i>Diabetes<\/i>:<\/p>\n<p>The figure shows visceral white adipose tissue in mice with adipocyte-specific deletion of <i>Fam20c<\/i> shifts shows lower macrophage area compared with controls.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Division of Cardiology, Department of Medicine, Weill Center for Metabolic Health, Cardiovascular Research Institute, and.<\/p>\n<p><sup>2<\/sup>Department of Medicine, Weill Cornell Medicine, New York, New York, USA.<\/p>\n<p><sup>3<\/sup>Helmholtz Institute for Metabolic, Obesity, and Vascular Research, Helmholtz Center Munich, University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here, James C. Lo &amp; team identify FAM20C as a key mediator of obesity-induced adipocyte dysfunction and inflammation, suggesting its inhibition as a potential therapy for Type2 Diabetes: The figure shows visceral white adipose tissue in mice with adipocyte-specific deletion of Fam20c shifts shows lower macrophage area compared with controls. 1Division of Cardiology, Department of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-228429","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228429"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228429\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}