{"id":228241,"date":"2026-01-02T22:13:31","date_gmt":"2026-01-03T04:13:31","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/potential-biomarker-linked-to-multiple-sclerosis-progression-and-brain-inflammation"},"modified":"2026-01-02T22:13:31","modified_gmt":"2026-01-03T04:13:31","slug":"potential-biomarker-linked-to-multiple-sclerosis-progression-and-brain-inflammation","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/potential-biomarker-linked-to-multiple-sclerosis-progression-and-brain-inflammation","title":{"rendered":"Potential biomarker linked to multiple sclerosis progression and brain inflammation"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/potential-biomarker-linked-to-multiple-sclerosis-progression-and-brain-inflammation.jpg\"><\/a><\/p>\n<p>A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.<\/p>\n<p>The findings were <a href=\"https:\/\/www.nature.com\/articles\/s41590-025-02359-5\" target=\"_blank\">published<\/a> today in <i>Nature Immunology<\/i> and validated in both mouse models and humans.<\/p>\n<p>\u201cWe think we have uncovered a potential biomarker that signals a patient is experiencing so-called \u2018compartmentalized inflammation\u2019 in the central nervous system, a phenomenon which is strongly linked to MS progression,\u201d says Jen Gommerman, a professor and chair of immunology at U of T\u2019s Temerty Faculty of Medicine. \u201cIt\u2019s been really hard to know who is progressing and who isn\u2019t.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs. The findings were published today in Nature Immunology and validated in both mouse models and humans. \u201cWe think we have uncovered a potential biomarker that [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-228241","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228241"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228241\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228241"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}