{"id":228168,"date":"2026-01-01T05:05:51","date_gmt":"2026-01-01T11:05:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/01\/a-protein-that-makes-hydrogen-sulfide-shows-potential-as-a-therapeutic-target-for-alzheimers-disease"},"modified":"2026-01-01T05:05:51","modified_gmt":"2026-01-01T11:05:51","slug":"a-protein-that-makes-hydrogen-sulfide-shows-potential-as-a-therapeutic-target-for-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/01\/a-protein-that-makes-hydrogen-sulfide-shows-potential-as-a-therapeutic-target-for-alzheimers-disease","title":{"rendered":"A protein that makes hydrogen sulfide shows potential as a therapeutic target for Alzheimer\u2019s disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-protein-that-makes-hydrogen-sulfide-shows-potential-as-a-therapeutic-target-for-alzheimers-disease.jpg\"><\/a><\/p>\n<p>Scientists at Johns Hopkins Medicine say results of a new study are advancing efforts to exploit a new target for Alzheimer\u2019s disease: a protein that manufactures an important gas in the brain.<\/p>\n<p>Experiments conducted in genetically engineered mice reinforce that the protein, Cystathionine \u03b3-lyase, or CSE\u2014ordinarily known for producing hydrogen sulfide gas responsible for the foul smell of rotten eggs\u2014is critical for memory formation, says Bindu Paul, M.S., Ph.D., associate professor of pharmacology, psychiatry and neuroscience at the Johns Hopkins University School of Medicine, who led the study.<\/p>\n<p>The new research, <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2528478122\" target=\"_blank\">published<\/a> in <i>Proceedings of the National Academy of Sciences<\/i>, was designed to better understand the basic biology of the protein, and its value as a novel target for drugs that boost the expression of CSE in people to help keep brain cells healthy and slow neurodegenerative disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists at Johns Hopkins Medicine say results of a new study are advancing efforts to exploit a new target for Alzheimer\u2019s disease: a protein that manufactures an important gas in the brain. Experiments conducted in genetically engineered mice reinforce that the protein, Cystathionine \u03b3-lyase, or CSE\u2014ordinarily known for producing hydrogen sulfide gas responsible for the [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-228168","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228168"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228168\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228168"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228168"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}