{"id":228154,"date":"2025-12-31T21:11:54","date_gmt":"2026-01-01T03:11:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/mathematicians-crack-cellular-noise-puzzle-paving-path-for-better-cancer-treatment"},"modified":"2025-12-31T21:11:54","modified_gmt":"2026-01-01T03:11:54","slug":"mathematicians-crack-cellular-noise-puzzle-paving-path-for-better-cancer-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/mathematicians-crack-cellular-noise-puzzle-paving-path-for-better-cancer-treatment","title":{"rendered":"Mathematicians crack cellular noise puzzle, paving path for better cancer treatment"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mathematicians-crack-cellular-noise-puzzle-paving-path-for-better-cancer-treatment2.jpg\"><\/a><\/p>\n<p>Why does cancer sometimes recur even after successful treatment, or why do some bacteria survive despite the use of powerful antibiotics? One of the key culprits identified is \u201cbiological noise\u201d\u2014random fluctuations occurring inside cells.<\/p>\n<p>Even when cells share the same genes, the amount of protein varies in each, creating \u201coutliers\u201d that evade drug treatments and survive. Until now, scientists could only control the average values of cell populations; controlling the irregular variability of individual cells remained a long-standing challenge.<\/p>\n<p>A joint research team\u2014led by Professor Jae Kyoung Kim (Department of Mathematical Sciences, KAIST), Professor Jinsu Kim (Department of Mathematics, POSTECH), and Professor Byung-Kwan Cho (Graduate School of Engineering Biology, KAIST)\u2014has theoretically established a \u201cnoise control principle.\u201d Through mathematical modeling, they have found a way to eliminate biological noise and precisely govern cellular destiny.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Why does cancer sometimes recur even after successful treatment, or why do some bacteria survive despite the use of powerful antibiotics? One of the key culprits identified is \u201cbiological noise\u201d\u2014random fluctuations occurring inside cells. Even when cells share the same genes, the amount of protein varies in each, creating \u201coutliers\u201d that evade drug treatments and [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,2229],"tags":[],"class_list":["post-228154","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-mathematics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228154","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228154"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228154\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228154"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228154"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228154"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}