{"id":228085,"date":"2025-12-30T21:20:31","date_gmt":"2025-12-31T03:20:31","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/multi-omics-analyses-reveal-djtcf4-critical-for-proper-timing-of-differentiation-in-planarian-regeneration"},"modified":"2025-12-30T21:20:31","modified_gmt":"2025-12-31T03:20:31","slug":"multi-omics-analyses-reveal-djtcf4-critical-for-proper-timing-of-differentiation-in-planarian-regeneration","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/multi-omics-analyses-reveal-djtcf4-critical-for-proper-timing-of-differentiation-in-planarian-regeneration","title":{"rendered":"Multi-omics analyses reveal DjTcf4 critical for proper timing of differentiation in planarian regeneration"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/multi-omics-analyses-reveal-djtcf4-critical-for-proper-timing-of-differentiation-in-planarian-regeneration2.jpg\"><\/a><\/p>\n<p>Wang et al. integrated ST-seq, scRNA-seq, and scATAC-seq data to profile transcriptional and chromatin dynamics in <i>D. <i>japonica<\/i><\/i> head blastema at 5 dpa. They pinpointed the <i>DjTcf4<\/i> gene network acting as a master transcription regulator to ensure cells rebuild complex structures like eyes in the right place and time.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wang et al. integrated ST-seq, scRNA-seq, and scATAC-seq data to profile transcriptional and chromatin dynamics in D. japonica head blastema at 5 dpa. They pinpointed the DjTcf4 gene network acting as a master transcription regulator to ensure cells rebuild complex structures like eyes in the right place and time.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-228085","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228085","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228085"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228085\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228085"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228085"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228085"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}