{"id":228074,"date":"2025-12-30T18:06:23","date_gmt":"2025-12-31T00:06:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/cleaving-mechanically-stressed-dna"},"modified":"2025-12-30T18:06:23","modified_gmt":"2025-12-31T00:06:23","slug":"cleaving-mechanically-stressed-dna","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/cleaving-mechanically-stressed-dna","title":{"rendered":"Cleaving mechanically stressed DNA"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cleaving-mechanically-stressed-dna.jpg\"><\/a><\/p>\n<p>Wang and Wu et al. identify soluble interleukin-6 receptor (sIL-6R) as a key exerkine determining the efficacy of exercise in diabetes prevention, which is modulated by microbiome-dependent leucine through a gut-adipose tissue axis. Pharmacological or dietary interventions targeting adipocyte-secreted sIL-6R may help to improve the metabolic outcomes in those exercise non-responders.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wang and Wu et al. identify soluble interleukin-6 receptor (sIL-6R) as a key exerkine determining the efficacy of exercise in diabetes prevention, which is modulated by microbiome-dependent leucine through a gut-adipose tissue axis. Pharmacological or dietary interventions targeting adipocyte-secreted sIL-6R may help to improve the metabolic outcomes in those exercise non-responders.<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-228074","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=228074"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/228074\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=228074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=228074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=228074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}