{"id":227974,"date":"2025-12-28T21:11:30","date_gmt":"2025-12-29T03:11:30","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/endothelial-il-36-receptor-activation-promotes-vascular-stability-to-limit-pathological-microvessel-permeability-in-the-cns"},"modified":"2025-12-28T21:11:30","modified_gmt":"2025-12-29T03:11:30","slug":"endothelial-il-36-receptor-activation-promotes-vascular-stability-to-limit-pathological-microvessel-permeability-in-the-cns","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/endothelial-il-36-receptor-activation-promotes-vascular-stability-to-limit-pathological-microvessel-permeability-in-the-cns","title":{"rendered":"Endothelial IL-36 receptor activation promotes vascular stability to limit pathological microvessel permeability in the CNS"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/endothelial-il-36-receptor-activation-promotes-vascular-stability-to-limit-pathological-microvessel-permeability-in-the-cns2.jpg\"><\/a><\/p>\n<p>Only a small number of barrier-enhancing factors have been discovered to specifically increase barrier integrity, enhance vessel stability, and make vessels resistant to fluid leakage. Here, Fahey et al. present DEVDIL-36\u03b2 as a cytokine promoter of vascular integrity in the CNS, with barrier-enhancing properties through upregulation of junctional components.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Only a small number of barrier-enhancing factors have been discovered to specifically increase barrier integrity, enhance vessel stability, and make vessels resistant to fluid leakage. Here, Fahey et al. present DEVDIL-36\u03b2 as a cytokine promoter of vascular integrity in the CNS, with barrier-enhancing properties through upregulation of junctional components.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-227974","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227974"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227974\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}