{"id":227911,"date":"2025-12-27T13:11:15","date_gmt":"2025-12-27T19:11:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/tenascin-c-from-the-tissue-microenvironment-promotes-muscle-stem-cell-maintenance-and-function-through-annexin-a2"},"modified":"2025-12-27T13:11:15","modified_gmt":"2025-12-27T19:11:15","slug":"tenascin-c-from-the-tissue-microenvironment-promotes-muscle-stem-cell-maintenance-and-function-through-annexin-a2","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/tenascin-c-from-the-tissue-microenvironment-promotes-muscle-stem-cell-maintenance-and-function-through-annexin-a2","title":{"rendered":"Tenascin-C from the tissue microenvironment promotes muscle stem cell maintenance and function through Annexin A2"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/tenascin-c-from-the-tissue-microenvironment-promotes-muscle-stem-cell-maintenance-and-function-through-annexin-a2.jpg\"><\/a><\/p>\n<p>Tenascin-C (TnC) produced by the fibro-adipogenic progenitors (FAPs) is required for MuSC maintenance and function. FAP-secreted TnC signals through Annexin-A2 on the MuSC surface to promote self-renewal and regeneration potential.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tenascin-C (TnC) produced by the fibro-adipogenic progenitors (FAPs) is required for MuSC maintenance and function. FAP-secreted TnC signals through Annexin-A2 on the MuSC surface to promote self-renewal and regeneration potential.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-227911","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227911","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227911"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227911\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227911"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227911"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227911"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}