{"id":227905,"date":"2025-12-27T05:09:33","date_gmt":"2025-12-27T11:09:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/therapeutic-vegfc-treatment-provides-protection-against-traumatic-brain-injury-driven-tauopathy-pathogenesis"},"modified":"2025-12-27T05:09:33","modified_gmt":"2025-12-27T11:09:33","slug":"therapeutic-vegfc-treatment-provides-protection-against-traumatic-brain-injury-driven-tauopathy-pathogenesis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/therapeutic-vegfc-treatment-provides-protection-against-traumatic-brain-injury-driven-tauopathy-pathogenesis","title":{"rendered":"Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/therapeutic-vegfc-treatment-provides-protection-against-traumatic-brain-injury-driven-tauopathy-pathogenesis2.jpg\"><\/a><\/p>\n<p>How traumatic brain injury (TBI) mechanistically contributes to neurodegenerative disease remains poorly understood. Marco et al. find that therapeutic viral vector-based delivery of VEGFC recuperates meningeal lymphatic drainage deficits post-TBI and protects against severe development of tauopathy, neurodegeneration, and cognitive decline in the PS19 mouse model of tauopathy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>How traumatic brain injury (TBI) mechanistically contributes to neurodegenerative disease remains poorly understood. Marco et al. find that therapeutic viral vector-based delivery of VEGFC recuperates meningeal lymphatic drainage deficits post-TBI and protects against severe development of tauopathy, neurodegeneration, and cognitive decline in the PS19 mouse model of tauopathy.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-227905","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227905"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227905\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}