{"id":227823,"date":"2025-12-26T01:42:02","date_gmt":"2025-12-26T07:42:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/rem-sleep-reduces-subthreshold-depolarization-in-cortical-pyramidal-neurons-in-a-region-specific-manner"},"modified":"2025-12-26T01:42:02","modified_gmt":"2025-12-26T07:42:02","slug":"rem-sleep-reduces-subthreshold-depolarization-in-cortical-pyramidal-neurons-in-a-region-specific-manner","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/rem-sleep-reduces-subthreshold-depolarization-in-cortical-pyramidal-neurons-in-a-region-specific-manner","title":{"rendered":"REM sleep reduces subthreshold depolarization in cortical pyramidal neurons in a region-specific manner"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rem-sleep-reduces-subthreshold-depolarization-in-cortical-pyramidal-neurons-in-a-region-specific-manner2.jpg\"><\/a><\/p>\n<p>Campelo et al. show that REM sleep induces region-specific changes in cortical excitability, with NMDARs playing a crucial role. Diazepam-induced sleep differs from natural sleep by disrupting normal inhibitory circuits, suggesting that hypnotic drugs may compromise sleep-dependent brain functions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Campelo et al. show that REM sleep induces region-specific changes in cortical excitability, with NMDARs playing a crucial role. Diazepam-induced sleep differs from natural sleep by disrupting normal inhibitory circuits, suggesting that hypnotic drugs may compromise sleep-dependent brain functions.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-227823","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227823"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227823\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}