{"id":227812,"date":"2025-12-25T09:09:34","date_gmt":"2025-12-25T15:09:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/creatine-kinase-b-regulates-glycolysis-and-de-novo-lipogenesis-pathways-to-control-lipid-accumulation-during-adipogenesis"},"modified":"2025-12-25T09:09:34","modified_gmt":"2025-12-25T15:09:34","slug":"creatine-kinase-b-regulates-glycolysis-and-de-novo-lipogenesis-pathways-to-control-lipid-accumulation-during-adipogenesis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/creatine-kinase-b-regulates-glycolysis-and-de-novo-lipogenesis-pathways-to-control-lipid-accumulation-during-adipogenesis","title":{"rendered":"Creatine kinase B regulates glycolysis and de novo lipogenesis pathways to control lipid accumulation during adipogenesis"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/creatine-kinase-b-regulates-glycolysis-and-de-novo-lipogenesis-pathways-to-control-lipid-accumulation-during-adipogenesis2.jpg\"><\/a><\/p>\n<p>Renzi et al. identify creatine kinase B (CKB) as a metabolic sensor during white adipocyte differentiation. By modulating AKT, CKB fine-tunes insulin signaling and glycolysis to restrain ChREBP activation, thereby controlling <i>de novo<\/i> lipogenesis. This work links creatine metabolism to nutrient-responsive transcriptional regulation of lipid accumulation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Renzi et al. identify creatine kinase B (CKB) as a metabolic sensor during white adipocyte differentiation. By modulating AKT, CKB fine-tunes insulin signaling and glycolysis to restrain ChREBP activation, thereby controlling de novo lipogenesis. This work links creatine metabolism to nutrient-responsive transcriptional regulation of lipid accumulation.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1694],"tags":[],"class_list":["post-227812","post","type-post","status-publish","format-standard","hentry","category-electronics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227812"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227812\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227812"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227812"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}