{"id":227781,"date":"2025-12-24T17:05:14","date_gmt":"2025-12-24T23:05:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/the-force-sensing-gpcr-lphn2-is-indispensable-for-normal-auditory-function"},"modified":"2025-12-24T17:05:14","modified_gmt":"2025-12-24T23:05:14","slug":"the-force-sensing-gpcr-lphn2-is-indispensable-for-normal-auditory-function","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/the-force-sensing-gpcr-lphn2-is-indispensable-for-normal-auditory-function","title":{"rendered":"The force-sensing GPCR LPHN2 is indispensable for normal auditory function"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-force-sensing-gpcr-lphn2-is-indispensable-for-normal-auditory-function2.jpg\"><\/a><\/p>\n<p>The mechanosensitive LPHN2 expressed at the tips of stereocilia in cochlear hair cells is identified as a modulator in the auditory process by interacting with MET channel components, which contributes to the Ca2+ response and neurotransmitter release in cochlear hair cells in response to mechanical stimulation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The mechanosensitive LPHN2 expressed at the tips of stereocilia in cochlear hair cells is identified as a modulator in the auditory process by interacting with MET channel components, which contributes to the Ca2+ response and neurotransmitter release in cochlear hair cells in response to mechanical stimulation.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-227781","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227781"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227781\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227781"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227781"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}