{"id":227626,"date":"2025-12-22T17:08:58","date_gmt":"2025-12-22T23:08:58","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/new-nanoparticles-stimulate-the-immune-system-to-attack-ovarian-tumors"},"modified":"2025-12-22T17:08:58","modified_gmt":"2025-12-22T23:08:58","slug":"new-nanoparticles-stimulate-the-immune-system-to-attack-ovarian-tumors","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/new-nanoparticles-stimulate-the-immune-system-to-attack-ovarian-tumors","title":{"rendered":"New nanoparticles stimulate the immune system to attack ovarian tumors"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-nanoparticles-stimulate-the-immune-system-to-attack-ovarian-tumors.jpg\"><\/a><\/p>\n<p>A team, including researchers in MIT ChemE, designed new nanoparticles that can deliver an immune-stimulating molecule called IL-12 directly to ovarian tumors. When given along with immunotherapy drugs called checkpoint inhibitors, IL-12 helps the immune system launch an attack on cancer cells.<\/p>\n<p>\u201cWhat\u2019s really exciting is that we\u2019re able to deliver IL-12 directly in the tumor space. And because of the way that this nanomaterial is designed to allow IL-12 to be borne on the surfaces of the cancer cells, we have essentially tricked the cancer into stimulating immune cells to arm themselves against that cancer,\u201d says MIT ChemE Professor Paula Hammond, a senior author of the study.<\/p>\n<p>\ud83d\udcf8: Courtesy of the researchers.<\/p>\n<hr>\n<p>MIT researchers designed nanoparticles that can deliver an immune-stimulating molecule called IL-12 directly to ovarian tumors. When given to mice along with checkpoint inhibitors, the treatment eliminated metastatic tumors more than 80 percent of the time.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team, including researchers in MIT ChemE, designed new nanoparticles that can deliver an immune-stimulating molecule called IL-12 directly to ovarian tumors. When given along with immunotherapy drugs called checkpoint inhibitors, IL-12 helps the immune system launch an attack on cancer cells. \u201cWhat\u2019s really exciting is that we\u2019re able to deliver IL-12 directly in the [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,4],"tags":[],"class_list":["post-227626","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227626","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227626"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227626\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}