{"id":227390,"date":"2025-12-18T10:18:07","date_gmt":"2025-12-18T16:18:07","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/plakophilin-3-drives-acinar-cell-transformation-and-promotes-cancer-initiation-and-progression-in-pancreas"},"modified":"2025-12-18T10:18:07","modified_gmt":"2025-12-18T16:18:07","slug":"plakophilin-3-drives-acinar-cell-transformation-and-promotes-cancer-initiation-and-progression-in-pancreas","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/plakophilin-3-drives-acinar-cell-transformation-and-promotes-cancer-initiation-and-progression-in-pancreas","title":{"rendered":"Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/plakophilin-3-drives-acinar-cell-transformation-and-promotes-cancer-initiation-and-progression-in-pancreas2.jpg\"><\/a><\/p>\n<p>Xiaojia Li et al. demonstrated that Plakophilin 3 is transformed from a structural protein into an oncogenic molecule, driving acinar cell transformation and promoting cancer initiation and progression in the pancreas through FOXM1 protein stabilization.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Xiaojia Li et al. demonstrated that Plakophilin 3 is transformed from a structural protein into an oncogenic molecule, driving acinar cell transformation and promoting cancer initiation and progression in the pancreas through FOXM1 protein stabilization.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-227390","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227390","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=227390"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/227390\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=227390"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=227390"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=227390"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}