{"id":226411,"date":"2025-12-03T12:13:42","date_gmt":"2025-12-03T18:13:42","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/mit-chemists-synthesize-a-fungal-compound-that-holds-promise-for-treating-brain-cancer"},"modified":"2025-12-03T12:13:42","modified_gmt":"2025-12-03T18:13:42","slug":"mit-chemists-synthesize-a-fungal-compound-that-holds-promise-for-treating-brain-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/mit-chemists-synthesize-a-fungal-compound-that-holds-promise-for-treating-brain-cancer","title":{"rendered":"MIT chemists synthesize a fungal compound that holds promise for treating brain cancer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mit-chemists-synthesize-a-fungal-compound-that-holds-promise-for-treating-brain-cancer2.jpg\"><\/a><\/p>\n<p>\u201cWe have a much better appreciation for how those subtle structural changes can significantly increase the synthetic challenge,\u201d says <a href=\"https:\/\/chemistry.mit.edu\/profile\/mohammad-movassaghi\/\">Mohammad Movassaghi<\/a>, an MIT professor of chemistry. \u201cNow we have the technology where we can not only access them for the first time, more than 50 years after they were isolated, but also we can make many designed variants, which can enable further detailed studies.\u201d<\/p>\n<p>In tests in human cancer cells, a derivative of verticillin A showed particular promise against a type of pediatric brain cancer called diffuse midline glioma. More tests will be needed to evaluate its potential for clinical use, the researchers say.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cWe have a much better appreciation for how those subtle structural changes can significantly increase the synthetic challenge,\u201d says Mohammad Movassaghi, an MIT professor of chemistry. \u201cNow we have the technology where we can not only access them for the first time, more than 50 years after they were isolated, but also we can make [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-226411","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226411","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=226411"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226411\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=226411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=226411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=226411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}