{"id":226388,"date":"2025-12-03T00:47:04","date_gmt":"2025-12-03T06:47:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/single-nucleotide-smn1-variants-in-a-cohort-of-individuals-with-spinal-muscular-atrophy"},"modified":"2025-12-03T00:47:04","modified_gmt":"2025-12-03T06:47:04","slug":"single-nucleotide-smn1-variants-in-a-cohort-of-individuals-with-spinal-muscular-atrophy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/single-nucleotide-smn1-variants-in-a-cohort-of-individuals-with-spinal-muscular-atrophy","title":{"rendered":"Single Nucleotide SMN1 Variants in a Cohort of Individuals With Spinal Muscular Atrophy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/single-nucleotide-smn1-variants-in-a-cohort-of-individuals-with-spinal-muscular-atrophy2.jpg\"><\/a><\/p>\n<p>Background and ObjectivesSpinal muscular atrophy 5q (SMA) is a motor neuron disorder caused by recessive pathogenic variants in the SMN1 gene, which encodes the survival motor neuron (SMN) protein. While the majority of patients with SMA exhibit\u2026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background and ObjectivesSpinal muscular atrophy 5q (SMA) is a motor neuron disorder caused by recessive pathogenic variants in the SMN1 gene, which encodes the survival motor neuron (SMN) protein. While the majority of patients with SMA exhibit\u2026<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-226388","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=226388"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226388\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=226388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=226388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=226388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}