{"id":226243,"date":"2025-12-01T12:16:26","date_gmt":"2025-12-01T18:16:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/new-breakthrough-to-strengthen-bone-could-reverse-osteoporosis"},"modified":"2025-12-01T12:16:26","modified_gmt":"2025-12-01T18:16:26","slug":"new-breakthrough-to-strengthen-bone-could-reverse-osteoporosis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/new-breakthrough-to-strengthen-bone-could-reverse-osteoporosis","title":{"rendered":"New Breakthrough to Strengthen Bone Could Reverse Osteoporosis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-breakthrough-to-strengthen-bone-could-reverse-osteoporosis.jpg\"><\/a><\/p>\n<p>A recent study points to a key bone-strengthening mechanism at work in the body, which could be targeted to treat the <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/osteoporosis\/symptoms-causes\/syc-20351968\">bone-weakening disease, osteoporosis<\/a>.<\/p>\n<p>Led by researchers from the University of Leipzig in Germany and Shandong University in China, the study identified the cell receptor GPR133 (also known as ADGRD1) as being crucial to bone density, via bone-building cells <a href=\"https:\/\/en.wikipedia.org\/wiki\/Osteoblast\">called osteoblasts<\/a>.<\/p>\n<p>Variations in the <em>GPR133<\/em> gene had previously <a href=\"https:\/\/doi.org\/10.1016\/j.celrep.2020.108145\">been linked<\/a> to bone density, leading scientists to turn their attention to the protein it encoded.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent study points to a key bone-strengthening mechanism at work in the body, which could be targeted to treat the bone-weakening disease, osteoporosis. Led by researchers from the University of Leipzig in Germany and Shandong University in China, the study identified the cell receptor GPR133 (also known as ADGRD1) as being crucial to bone [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1522],"tags":[],"class_list":["post-226243","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-innovation"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226243","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=226243"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226243\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=226243"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=226243"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=226243"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}