{"id":226241,"date":"2025-12-01T12:15:27","date_gmt":"2025-12-01T18:15:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/immunological-biomarkers-in-autism-spectrum-disorder-the-role-of-tnf-alpha-and-dependent-trends-in-serum-il-6-and-cxcl8"},"modified":"2025-12-01T12:15:27","modified_gmt":"2025-12-01T18:15:27","slug":"immunological-biomarkers-in-autism-spectrum-disorder-the-role-of-tnf-alpha-and-dependent-trends-in-serum-il-6-and-cxcl8","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/immunological-biomarkers-in-autism-spectrum-disorder-the-role-of-tnf-alpha-and-dependent-trends-in-serum-il-6-and-cxcl8","title":{"rendered":"Immunological Biomarkers in Autism Spectrum Disorder: The Role of TNF-Alpha and Dependent Trends in Serum IL-6 and CXCL8"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/immunological-biomarkers-in-autism-spectrum-disorder-the-role-of-tnf-alpha-and-dependent-trends-in-serum-il-6-and-cxcl82.jpg\"><\/a><\/p>\n<p>Background: Autism spectrum disorder (ASD) has seen a rise in prevalence, and the immune system\u2019s role in brain development is increasingly recognized. This study investigates the relationship between immune dysregulation and ASD by examining serum concentrations of interleukin 6 (IL-6), interleukin 8 (CXCL8), and tumor necrosis factor alpha (TNF-alpha) in children. Methods: Serum samples from 45 children with ASD and 30 controls, aged 2 to 12 years, were analyzed using electrochemiluminescence, chemiluminescent microparticle immunoassay, and chemiluminescent immunoassay. ASD symptoms were assessed using the Autism Spectrum Rating Scale (ASRS) and Social Communication Questionnaire (SCQ). Results: No significant correlation was observed between CXCL8 levels and ASD. IL-6 levels showed a trend toward elevation in boys with ASD.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background: Autism spectrum disorder (ASD) has seen a rise in prevalence, and the immune system\u2019s role in brain development is increasingly recognized. This study investigates the relationship between immune dysregulation and ASD by examining serum concentrations of interleukin 6 (IL-6), interleukin 8 (CXCL8), and tumor necrosis factor alpha (TNF-alpha) in children. Methods: Serum samples from [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-226241","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=226241"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226241\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=226241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=226241"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=226241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}