{"id":226239,"date":"2025-12-01T12:13:57","date_gmt":"2025-12-01T18:13:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/12\/antibody-evasion-and-receptor-binding-of-sars-cov-2-lp-8-1-1-nb-1-8-1-xfg-and-related-subvariants"},"modified":"2025-12-01T12:13:57","modified_gmt":"2025-12-01T18:13:57","slug":"antibody-evasion-and-receptor-binding-of-sars-cov-2-lp-8-1-1-nb-1-8-1-xfg-and-related-subvariants","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/12\/antibody-evasion-and-receptor-binding-of-sars-cov-2-lp-8-1-1-nb-1-8-1-xfg-and-related-subvariants","title":{"rendered":"Antibody evasion and receptor binding of SARS-CoV-2 LP.8.1.1, NB.1.8.1, XFG, and related subvariants"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/antibody-evasion-and-receptor-binding-of-sars-cov-2-lp-8-1-1-nb-1-8-1-xfg-and-related-subvariants2.jpg\"><\/a><\/p>\n<p>Mellis et al. show that the SARS-CoV-2 JN.1 sublineage has different virological features associated with its recently dominant subvariants. LP.8.1 has greater receptor-binding affinity than earlier strains but not increased antibody evasion, while the more recently dominant XFG and NB.1.8.1 have greater antibody evasion than LP.8.1.1.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mellis et al. show that the SARS-CoV-2 JN.1 sublineage has different virological features associated with its recently dominant subvariants. LP.8.1 has greater receptor-binding affinity than earlier strains but not increased antibody evasion, while the more recently dominant XFG and NB.1.8.1 have greater antibody evasion than LP.8.1.1.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-226239","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=226239"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226239\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=226239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=226239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=226239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}