{"id":226002,"date":"2025-11-27T00:27:36","date_gmt":"2025-11-27T06:27:36","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/possible-therapeutic-approach-to-treat-diabetic-nerve-damage-discovered"},"modified":"2025-11-27T00:27:36","modified_gmt":"2025-11-27T06:27:36","slug":"possible-therapeutic-approach-to-treat-diabetic-nerve-damage-discovered","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/possible-therapeutic-approach-to-treat-diabetic-nerve-damage-discovered","title":{"rendered":"Possible therapeutic approach to treat diabetic nerve damage discovered"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/possible-therapeutic-approach-to-treat-diabetic-nerve-damage-discovered2.jpg\"><\/a><\/p>\n<p>Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from pain, numbness, and restricted movement, largely because damaged nerve fibers do not regenerate sufficiently. The reasons for this are unclear.<\/p>\n<p>A research team led by Professor Dr. Dietmar Fischer, Professor of Pharmacology at the University of Cologne\u2019s Faculty of Medicine, and Director of the Center for Pharmacology at University Hospital Cologne, has now identified a central mechanism that explains limited regeneration in diabetes.<\/p>\n<p>Building on this, the researchers have developed a promising therapeutic approach that can be used to increase regeneration. Their findings were published in the <i>Science Translational Medicine<\/i> journal under the title \u201cFailure of nerve regeneration in mouse models of diabetes is caused by p35-mediated CDK5 hyperactivity.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from pain, numbness, and restricted movement, largely because damaged nerve fibers do not regenerate sufficiently. The reasons for this are unclear. A research team led by Professor Dr. Dietmar Fischer, Professor of Pharmacology at the University of [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-226002","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=226002"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/226002\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=226002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=226002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=226002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}