{"id":225566,"date":"2025-11-21T01:34:39","date_gmt":"2025-11-21T07:34:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/aging-alters-the-protein-landscape-in-the-brain-diet-can-counteract-this"},"modified":"2025-11-21T01:34:39","modified_gmt":"2025-11-21T07:34:39","slug":"aging-alters-the-protein-landscape-in-the-brain-diet-can-counteract-this","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/aging-alters-the-protein-landscape-in-the-brain-diet-can-counteract-this","title":{"rendered":"Aging alters the protein landscape in the brain \u2014 diet can counteract this"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/aging-alters-the-protein-landscape-in-the-brain-diet-can-counteract-this.jpg\"><\/a><\/p>\n<p>A study by the Leibniz Institute on Aging \u2013 Fritz Lipmann Institute (FLI) in Jena shows that the chemical composition of proteins in the brain undergoes fundamental changes with aging. In particular, ubiquitylation\u2014a process that marks proteins and thus controls their activity and degradation\u2014undergoes drastic changes in the aging brain. Interestingly, a change in nutrition, such as short-term dietary restriction, can partially revert some of these molecular patterns. These findings open up new opportunities to better understand the aging process of the brain and related diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study by the Leibniz Institute on Aging \u2013 Fritz Lipmann Institute (FLI) in Jena shows that the chemical composition of proteins in the brain undergoes fundamental changes with aging. In particular, ubiquitylation\u2014a process that marks proteins and thus controls their activity and degradation\u2014undergoes drastic changes in the aging brain. Interestingly, a change in nutrition, [\u2026]<\/p>\n","protected":false},"author":701,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,269,47],"tags":[],"class_list":["post-225566","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225566","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/701"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=225566"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225566\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=225566"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=225566"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=225566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}