{"id":225539,"date":"2025-11-20T20:05:00","date_gmt":"2025-11-21T02:05:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/oxygen-deprivation-drives-dysfunctional-neutrophil-immunity"},"modified":"2025-11-20T20:05:00","modified_gmt":"2025-11-21T02:05:00","slug":"oxygen-deprivation-drives-dysfunctional-neutrophil-immunity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/oxygen-deprivation-drives-dysfunctional-neutrophil-immunity","title":{"rendered":"Oxygen deprivation drives dysfunctional neutrophil immunity"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/oxygen-deprivation-drives-dysfunctional-neutrophil-immunity2.jpg\"><\/a><\/p>\n<p>Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body\u2019s ability to fight infection, new research shows.<\/p>\n<p>Scientists found that oxygen deprivation \u2013 known as hypoxia \u2013 changes the genetic material of immune cells called neutrophils, reducing their capacity to destroy harmful microbes.<\/p>\n<p>The team discovered that low oxygen appears to leave a lasting mark on the bone marrow cells that produce neutrophils, meaning the impact can persist after oxygen levels return to normal.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body\u2019s ability to fight infection, new research shows. Scientists found that oxygen deprivation \u2013 known as hypoxia \u2013 changes the genetic material of immune cells called neutrophils, reducing their capacity to destroy harmful microbes. The team discovered that [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-225539","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225539","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=225539"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225539\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=225539"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=225539"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=225539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}