{"id":225319,"date":"2025-11-18T01:25:14","date_gmt":"2025-11-18T07:25:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/next-generation-microbiome-medicine-may-transform-parkinsons-treatment"},"modified":"2025-11-18T01:25:14","modified_gmt":"2025-11-18T07:25:14","slug":"next-generation-microbiome-medicine-may-transform-parkinsons-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/next-generation-microbiome-medicine-may-transform-parkinsons-treatment","title":{"rendered":"Next-generation microbiome medicine may transform Parkinson\u2019s treatment"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/next-generation-microbiome-medicine-may-transform-parkinsons-treatment.jpg\"><\/a><\/p>\n<p>The age-old advice to \u201ctrust your gut\u201d could soon take on new meaning for people diagnosed with Parkinson\u2019s disease, thanks to a creative feat of bioengineering by researchers in the University of Georgia\u2019s College of Veterinary Medicine.<\/p>\n<p>Anumantha Kanthasamy, professor and director of the Isakson Center for Neurological Disease Research (ICNDR) leads a multidisciplinary research team including Gregory Phillips, Piyush Padhi, and other scientists that has engineered a groundbreaking living medicine, a beneficial probiotic designed to deliver levodopa steadily from the gut to the brain of Parkinson\u2019s patients.<\/p>\n<p>In a <a href=\"https:\/\/doi.org\/10.1016\/j.chom.2025.10.005\" target=\"_blank\">paper<\/a> published in the journal <i>Cell Host &amp; Microbe<\/i>, Kanthasamy\u2019s team details how they engineered and tested the probiotic bacterium Escherichia coli Nissle 1917 as a drug-delivery system that continuously produces and delivers the gold-standard Parkinson\u2019s drug, which is converted to dopamine in the brain. The E. coli Nissle strain was chosen for its century-long record of safely treating gastrointestinal disorders in humans.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The age-old advice to \u201ctrust your gut\u201d could soon take on new meaning for people diagnosed with Parkinson\u2019s disease, thanks to a creative feat of bioengineering by researchers in the University of Georgia\u2019s College of Veterinary Medicine. Anumantha Kanthasamy, professor and director of the Isakson Center for Neurological Disease Research (ICNDR) leads a multidisciplinary research [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,47],"tags":[],"class_list":["post-225319","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225319","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=225319"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225319\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=225319"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=225319"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=225319"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}