{"id":225057,"date":"2025-11-13T21:11:10","date_gmt":"2025-11-14T03:11:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/co-translational-protein-aggregation-and-ribosome-stalling-as-a-broad-spectrum-antibacterial-mechanism"},"modified":"2025-11-13T21:11:10","modified_gmt":"2025-11-14T03:11:10","slug":"co-translational-protein-aggregation-and-ribosome-stalling-as-a-broad-spectrum-antibacterial-mechanism","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/co-translational-protein-aggregation-and-ribosome-stalling-as-a-broad-spectrum-antibacterial-mechanism","title":{"rendered":"Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/co-translational-protein-aggregation-and-ribosome-stalling-as-a-broad-spectrum-antibacterial-mechanism.jpg\"><\/a><\/p>\n<p>Protein biosynthesis is a major target of existing antibiotics that inhibit the efficiency or fidelity of the bacterial ribosome. Here, the authors show that a synthetic peptide displays bactericidal activity through a different mechanism, inducing co-translational aggregation of nascent peptidic chains.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Protein biosynthesis is a major target of existing antibiotics that inhibit the efficiency or fidelity of the bacterial ribosome. Here, the authors show that a synthetic peptide displays bactericidal activity through a different mechanism, inducing co-translational aggregation of nascent peptidic chains.<\/p>\n","protected":false},"author":636,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-225057","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225057","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/636"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=225057"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225057\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=225057"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=225057"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=225057"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}