{"id":225047,"date":"2025-11-13T21:04:00","date_gmt":"2025-11-14T03:04:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/scientists-map-the-brains-construction-from-stem-cells-to-early-adolescence"},"modified":"2025-11-13T21:04:00","modified_gmt":"2025-11-14T03:04:00","slug":"scientists-map-the-brains-construction-from-stem-cells-to-early-adolescence","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/scientists-map-the-brains-construction-from-stem-cells-to-early-adolescence","title":{"rendered":"Scientists Map the Brain\u2019s Construction From Stem Cells to Early Adolescence"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-map-the-brains-construction-from-stem-cells-to-early-adolescence2.jpg\"><\/a><\/p>\n<p>This herculean effort could help scientists unravel the causes of neurodevelopmental disorders. <a href=\"https:\/\/www.nature.com\/articles\/s41586-024-08351-7\">In one study<\/a>, led by Arnold Kriegstein at the University of California, San Francisco, scientists found brain stem cells that are potentially co-opted to form a deadly brain cancer in adulthood. Other studies shed light on imbalances between excitatory and inhibitory neurons\u2014these ramp up or tone down brain activity, respectively\u2014which could contribute to <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26291155\/\">autism<\/a> and <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22355184\/\">schizophrenia<\/a>.<\/p>\n<p>\u201cMany brain diseases begin during different stages of development, but until now we haven\u2019t had a comprehensive roadmap for simply understanding healthy brain development,\u201d <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1069907\">said<\/a> Kriegstein in a press release. \u201cOur map highlights the genetic programs behind the growth of the human brain that go awry during specific forms of brain dysfunction.\u201d<\/p>\n<p>Over a century ago, the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Santiago_Ram%C3%B3n_y_Cajal\">first neuroscientists<\/a> used brain cell shapes to categorize their identities. BICAN collaborators have a much larger arsenal of tools to <a href=\"https:\/\/singularityhub.com\/2025\/04\/14\/largest-brain-map-ever-reveals-hidden-algorithms-of-the-mammalian-brain\/\">map the brain\u2019s cells<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This herculean effort could help scientists unravel the causes of neurodevelopmental disorders. In one study, led by Arnold Kriegstein at the University of California, San Francisco, scientists found brain stem cells that are potentially co-opted to form a deadly brain cancer in adulthood. Other studies shed light on imbalances between excitatory and inhibitory neurons\u2014these ramp [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-225047","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=225047"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225047\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=225047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=225047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=225047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}