{"id":225023,"date":"2025-11-13T05:16:17","date_gmt":"2025-11-13T11:16:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/the-promise-and-pitfalls-of-polygenic-risk-scores"},"modified":"2025-11-13T05:16:17","modified_gmt":"2025-11-13T11:16:17","slug":"the-promise-and-pitfalls-of-polygenic-risk-scores","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/the-promise-and-pitfalls-of-polygenic-risk-scores","title":{"rendered":"The Promise and Pitfalls of Polygenic Risk Scores"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-promise-and-pitfalls-of-polygenic-risk-scores.jpg\"><\/a><\/p>\n<p>Polygenic risk scores estimate genetic predisposition to complex diseases by combining thousands of DNA variants. Dr. Anna CF Lewis of Harvard Medical School discusses their promise for personalized medicine and the ethical challenges they raise.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Polygenic risk scores estimate genetic predisposition to complex diseases by combining thousands of DNA variants. Dr. Anna CF Lewis of Harvard Medical School discusses their promise for personalized medicine and the ethical challenges they raise.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-225023","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225023","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=225023"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/225023\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=225023"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=225023"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=225023"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}