{"id":224969,"date":"2025-11-12T13:07:10","date_gmt":"2025-11-12T19:07:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/newly-discovered-rna-molecule-could-limit-protein-aggregation-and-prevent-neuronal-damage"},"modified":"2025-11-12T13:07:10","modified_gmt":"2025-11-12T19:07:10","slug":"newly-discovered-rna-molecule-could-limit-protein-aggregation-and-prevent-neuronal-damage","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/newly-discovered-rna-molecule-could-limit-protein-aggregation-and-prevent-neuronal-damage","title":{"rendered":"Newly discovered RNA molecule could limit protein aggregation and prevent neuronal damage"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/newly-discovered-rna-molecule-could-limit-protein-aggregation-and-prevent-neuronal-damage2.jpg\"><\/a><\/p>\n<p>Neurodegenerative diseases, such as Alzheimer\u2019s disease and dementia, are medical conditions that entail the progressive loss of neurons and a decline in brain function. Past studies have found a link between these diseases and the buildup of misfolded proteins, such as tau and \u03b1-synuclein.<\/p>\n<p>Tau is a protein found primarily in neurons that typically helps to stabilize structures that transport nutrients and molecules within neurons, known as microtubules. \u03b1-synuclein, on the other hand, is a small protein located at the tips of neurons (i.e., pre-synapses), which typically helps to regulate the function of synaptic vesicles, small sacs that release neurotransmitters across synapses.<\/p>\n<p>While these proteins have an important function in the healthy brain, their abnormal <a href=\"https:\/\/medicalxpress.com\/tags\/aggregation\/\" rel=\"tag\" class=\"\">aggregation<\/a> has been found to be a hallmark of several neurodegenerative diseases. The <a href=\"https:\/\/medicalxpress.com\/tags\/molecular+processes\/\" rel=\"tag\" class=\"\">molecular processes<\/a> that prompt their accumulation, however, have not yet been fully elucidated.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neurodegenerative diseases, such as Alzheimer\u2019s disease and dementia, are medical conditions that entail the progressive loss of neurons and a decline in brain function. Past studies have found a link between these diseases and the buildup of misfolded proteins, such as tau and \u03b1-synuclein. Tau is a protein found primarily in neurons that typically helps [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-224969","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224969","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=224969"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224969\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=224969"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=224969"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=224969"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}