{"id":224933,"date":"2025-11-12T01:19:46","date_gmt":"2025-11-12T07:19:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/improved-method-offers-broader-faster-detection-of-protein-ligand-interactions"},"modified":"2025-11-12T01:19:46","modified_gmt":"2025-11-12T07:19:46","slug":"improved-method-offers-broader-faster-detection-of-protein-ligand-interactions","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/improved-method-offers-broader-faster-detection-of-protein-ligand-interactions","title":{"rendered":"Improved method offers broader, faster detection of protein-ligand interactions"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/improved-method-offers-broader-faster-detection-of-protein-ligand-interactions.jpg\"><\/a><\/p>\n<p>EMBL scientists have improved a protein analysis technique, significantly expanding its use and making it 100 times faster.<\/p>\n<p>Swedish chemist J\u00f6ns Jacob Berzelius, in a letter to a fellow chemist, first suggested the name \u201cproteins\u201d for a particular class of biological substances, deriving it from the Greek word proteios, meaning \u201cprimary\u201d or \u201cof first importance.\u201d Although scientists in the 1830s knew very little about proteins, it was already clear how essential they were to living organisms.<\/p>\n<p>Long-known as the \u201cworkhorses of the cell,\u201d proteins are responsible for powering nearly every function in the body. Often critical to this is their interactions with other small molecules known as ligands. In a <a href=\"https:\/\/www.nature.com\/articles\/s41594-025-01699-y\" target=\"_blank\">new study published in<\/a> <i>Nature Structural and Molecular Biology<\/i>, EMBL researchers introduce HT-PELSA, a high-throughput adaptation of an earlier tool that detects these interactions. This new tool can process samples at an unprecedented scale, a breakthrough that promises to accelerate <a href=\"https:\/\/phys.org\/tags\/drug+discovery\/\" rel=\"tag\" class=\"\">drug discovery<\/a> and our understanding of fundamental biological processes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>EMBL scientists have improved a protein analysis technique, significantly expanding its use and making it 100 times faster. Swedish chemist J\u00f6ns Jacob Berzelius, in a letter to a fellow chemist, first suggested the name \u201cproteins\u201d for a particular class of biological substances, deriving it from the Greek word proteios, meaning \u201cprimary\u201d or \u201cof first importance.\u201d [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1522],"tags":[],"class_list":["post-224933","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-innovation"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=224933"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224933\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=224933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=224933"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=224933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}