{"id":224653,"date":"2025-11-06T21:05:21","date_gmt":"2025-11-07T03:05:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/mit-researchers-invent-new-human-brain-model-to-enable-disease-research-drug-discovery"},"modified":"2025-11-06T21:05:21","modified_gmt":"2025-11-07T03:05:21","slug":"mit-researchers-invent-new-human-brain-model-to-enable-disease-research-drug-discovery","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/mit-researchers-invent-new-human-brain-model-to-enable-disease-research-drug-discovery","title":{"rendered":"MIT researchers invent new human brain model to enable disease research, drug discovery"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mit-researchers-invent-new-human-brain-model-to-enable-disease-research-drug-discovery.jpg\"><\/a><\/p>\n<p>A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells, and the vasculature, into a single culture.<\/p>\n<p>Grown from individual donors\u2019 induced pluripotent stem cells, these models \u2014 dubbed Multicellular Integrated Brains (miBrains) \u2014 replicate key features and functions of human brain tissue, are readily customizable through gene editing, and can be produced in quantities that support large-scale research.<\/p>\n<p>Although each unit is smaller than a dime, miBrains may be worth a great deal to researchers and drug developers who need more complex living lab models to better understand brain biology and treat diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells, and the vasculature, into a single culture. Grown from individual donors\u2019 induced pluripotent stem cells, these models \u2014 dubbed Multicellular Integrated Brains (miBrains) \u2014 replicate key features and functions of [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,47],"tags":[],"class_list":["post-224653","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=224653"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224653\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=224653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=224653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=224653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}