{"id":224588,"date":"2025-11-05T17:08:46","date_gmt":"2025-11-05T23:08:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/11\/micron-resolution-fiber-mapping-in-histology-independent-of-sample-preparation"},"modified":"2025-11-05T17:08:46","modified_gmt":"2025-11-05T23:08:46","slug":"micron-resolution-fiber-mapping-in-histology-independent-of-sample-preparation","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/11\/micron-resolution-fiber-mapping-in-histology-independent-of-sample-preparation","title":{"rendered":"Micron-resolution fiber mapping in histology independent of sample preparation"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/micron-resolution-fiber-mapping-in-histology-independent-of-sample-preparation.jpg\"><\/a><\/p>\n<p>To understand brain diseases, neuroscientists try to understand the intricate maze of nerve fibers in our brains. For analysis under a microscope, brain tissue is often immersed in paraffin wax to create high-quality slices. But until now, it has been impossible to precisely trace the densely packed nerves in these slices. Researchers from Delft, Stanford, J\u00fclich, and Rotterdam have achieved a milestone: using the ComSLI technique, they can now map the fibers in any tissue sample with micrometer precision. The research is published in <i>Nature<\/i> Communications.<\/p>\n<p> Micron-resolution fiber mapping in histology independent of sample preparation.<\/p>\n<hr>\n<p>Georgiadis and colleagues conduct micron-resolution fibre mapping on multiple histological tissue sections. Their light-scattering technique works across different sample preparations and tissue types, including formalin-fixed paraffin-embedded brain sections.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>To understand brain diseases, neuroscientists try to understand the intricate maze of nerve fibers in our brains. For analysis under a microscope, brain tissue is often immersed in paraffin wax to create high-quality slices. But until now, it has been impossible to precisely trace the densely packed nerves in these slices. Researchers from Delft, Stanford, [\u2026]<\/p>\n","protected":false},"author":701,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-224588","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224588","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/701"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=224588"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224588\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=224588"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=224588"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=224588"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}